Hepatitis B Testing Singapore | STD

Hepatitis B Testing in Singapore: Hepatitis B test Singapore: There are a variety of tests for Hepatitis B.

Abbreviation Name Presence in blood indicates
HBsAg Hepatitis B Surface Antigen
(Australia antigen)
HBsAb Hepatitis B Surface Antibody Immunity
HBeAg Hepatitis B Envelope Antigen Infectivity/Activity
HBeAb Hepatitis B Envelope Antibody Favourable prognosis
HBcAg Hepatitis B Core Antigen Not detectable in blood
Detectable in liver biopsy
HBcAb Hepatitis B Core Antibody HBsAb presence
due to infection

Blood testing is available for all the above except HBcAg






Serologic markers

The order of appearance of markers in acute infections is – HBsAg, HBeAg, antiHBc IgM, antiHBe, antiHBc IgG, antiHBs (Annex VI).

The significance of HBs antigen and antibody markers is shown below:

Marker Clinical Significance

HBsAg Presence of HBV
HBeAg Virus replication, High infectivity
Anti-HBc IgM Acute infection
Anti-HBc IgG Late acute or chronic infection
Anti-HBe Loss of replication, low infectivity
Anti-HBs Protective antibody



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