Hepatitis B Testing Singapore | STD

Hepatitis B Testing in Singapore: Hepatitis B test Singapore: There are a variety of tests for Hepatitis B.

Abbreviation Name Presence in blood indicates
HBsAg Hepatitis B Surface Antigen
(Australia antigen)
Carrier
HBsAb Hepatitis B Surface Antibody Immunity
HBeAg Hepatitis B Envelope Antigen Infectivity/Activity
HBeAb Hepatitis B Envelope Antibody Favourable prognosis
HBcAg Hepatitis B Core Antigen Not detectable in blood
Detectable in liver biopsy
HBcAb Hepatitis B Core Antibody HBsAb presence
due to infection

Blood testing is available for all the above except HBcAg

 

 

 


 

LABORATORY TESTS

Serologic markers

The order of appearance of markers in acute infections is – HBsAg, HBeAg, antiHBc IgM, antiHBe, antiHBc IgG, antiHBs (Annex VI).

The significance of HBs antigen and antibody markers is shown below:

Marker Clinical Significance

HBsAg Presence of HBV
HBeAg Virus replication, High infectivity
Anti-HBc IgM Acute infection
Anti-HBc IgG Late acute or chronic infection
Anti-HBe Loss of replication, low infectivity
Anti-HBs Protective antibody

 

 

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